Example 3) Determining job scheme processing order - explicit precursor schemes

This example shows what happens where explicit precursor schemes are in place.

Job Scheme Registration Sequence

Scheme

Explicit Precursor Scheme Relationships

1

Ana1

Ana1Prep

2

Ana3

x

3

Ana2

Ana2Prep

4

SamPrep1

x

5

SamPrep2

x

6

Ana1Prep

SamPrep1

7

Ana2Prep

SamPrep2

The system adds in implicit precursor scheme relationships for apply QC masks, based on the rule that any sample preparation scheme must be processed before any analytical preparation or analytical scheme so that QC samples created during sample preparation can propagate to all analytical preparation and analytical schemes:

For the process of applying QC masks to create QC samples

For the process of determining warning, expiry and ready date-times

Uses explicit precursor scheme relationships

AND

Uses implicit precursor scheme relationships

Uses explicit precursor scheme relationships only.

SamPrep1 --> Ana1Prep

SamPrep1 --> Ana2Prep (implicit)

SamPrep1 --> Ana1 (implicit)

SamPrep1 --> Ana3 (implicit)

SamPrep1 --> Ana2 (implicit)

SamPrep2 --> Ana1Prep (implicit)

SamPrep2 --> Ana2Prep

SamPrep2 --> Ana1 (implicit)

SamPrep2 --> Ana3 (implicit)

SamPrep2 --> Ana2 (implicit)

Ana1Prep --> Ana1

Ana2Prep --> Ana2

SamPrep1 --> Ana1Prep

SamPrep2 --> Ana2Prep

Ana1Prep --> Ana1

Ana2Prep --> Ana2

Therefore:

  • When QC samples are created using QC masks, then:
    • The job schemes are processed in job scheme sequence, but obey explicit and implicit precursor relationships: SamPrep1 --> SamPrep2 --> Ana1Prep --> Ana1 --> Ana3 --> Ana2Prep --> Ana2
    • QC samples created for SamPrep1, if flagged for propagation in the QC mask, is registered for Ana1Prep, Ana1, Ana3, Ana2Prep and Ana2 also (an exception is where the QC sample is a duplicate, replicate or spike but original sample does not exist in the destination scheme).
    • QC samples created for SamPrep2, if flagged for propagation in the QC mask, is registered for Ana1Prep, Ana1, Ana3, Ana2Prep and Ana2 also (an exception is where the QC sample is a duplicate, replicate or spike but original sample does not exist in the destination scheme).
    • QC samples created for Ana1Prep, if flagged for propagation in the QC mask, is registered for Ana1 also (an exception is where the QC sample is a duplicate, replicate or spike but original sample does not exist in the destination scheme).
    • QC samples created for Ana3 are not propagated as there are no sequel schemes.
    • QC samples created for Ana2Prep, if flagged for propagation in the QC mask, is registered for Ana2 also (an exception is where the QC sample is a duplicate, replicate or spike but original sample does not exist in the destination scheme).
  • Warning and expiry date-times is determined for Ana1 and Ana2 if holding times are defined.
  • Ready date-times is determined for Ana1Prep and Ana2Prep if waiting time is defined.