Configure QC Options for Analysis Codes

For context, see Configure Analysis Codes Options.

Activity Steps

  1. On the Profile ribbon tab, click Analysis Code.

    The Analysis Codes screen displays.

  2. Select the Analysis Code.
  3. On the menu, click Setup » Options.

    The Edit Analysis Code screen displays in the Client Job Options category group.

  4. In the Category list, click Q.C Options.

    The Q.C Options screen displays.

    Important: Before you modify the parameters in this section, it is critical to understand the calculation behind the replicate acceptance percentage variance. See QC Replicate Calculations. For further help, contact AssayNet support.

    1. In the Prep Splits category group, complete the following fields:
      • Show Prep Splits—Shows the calculations for the preparation duplicates (Prep Splits) and enables the rest of the fields.
      • Use Code for QC—Uses the Code in the sample split for QC naming.
      • Variance at Low Limit—Maximum allowable percentage variance when the concentration is at the analyte scheme detection limit.
      • Variance At—A factor that adjusts the allowable variance as concentrations increase. This parameter scales the detection limit to establish a new threshold for higher concentrations.
      • x Low Limit—This upper limit variance parameter defines the maximum allowable variance when the high concentration limit is N times the detection limit.
    2. In the Prep QC category group, complete the following fields:
      • Show Prep QC Samples—Shows the calculations for the preparation QC and enables the rest of the fields.
      • Variance at Low Limit
      • Variance At
      • x Low Limit

        Note: The Prep QC fields adjust the replicate acceptance variance for the Prep QC, which uses the same parameters and formula as the one in step 4 a. For more information, see Add a Prep QC Sample.

    3. In the Replicate category group, complete the following fields:

      Note: The Replicate fields adjust the replicate acceptance variance for the client sample replicates, which use the same parameters and formula as the ones in step 4 a and 4 b. These fields offer more options to calculate the variance between the samples and the allowable percentage variance at different concentrations.

      1. Show Replicates—Shows the calculations for the client sample replicates and enables the rest of the fields.
      2. To use the dynamic variance formula, see the QC Replicate Calculations activity.
        • Variance at Low Limit
        • Variance At
        • x Low Limit
      3. To use the alternative formula, which utilizes an exponential curve fit for replicate analysis:
        1. Click Use am^b for Precision.

          Fields a and b become available.

        2. Complete the following fields where a and b are user-defined parameters and M represents the absolute standard difference of the replicates.
      4. Select which replicate variance difference formula to use from:
        • Std. Diff.
        • % RSD
      5. To use a user-defined code name for the original and replicate sample if required:
        • Enter Original.
        • Enter Duplicate.

        Note: When the Original and Duplicate fields are left blank, AssayNet LIMS defaults to naming them using the Sample ID with (1) for the original and (2) for the duplicate.

    4. In the Method Blank category group, complete the following fields:
      • Show Method Blank—Shows the calculations for the method blank replicates and enables the rest of the fields.
      • Variance at—This factor determines the allowable variance by setting a multiplier on the detection limit. For example, if you want the allowable variance to be 20% above the detection limit, you would enter 1.2 as the value for Variance At.
      • Code—Changes the default method blank code (Method Blank) to a user-defined code.
      • Hide in Lab Job—Hides the method blank sample in the laboratory job (because no weight is captured for it), but still shows the sample ID and the calculation in the instrument run.
      • Measurement 1—Allows initial measurement input for the first measurement column.
      • Measurement 2—Allows initial measurement input for the second measurement column when available.
    5. In the Manual Data Entry category group for Instrument Run and Lab Job, select the desired data entry behavior from the following options:
      • Allow—Allows manual entry of the initial measurements.
      • Do not Allow—Does not allow manual entry of the initial measurements.
      • Required Comment—Requires entering a comment when entering the initial measurements manually.
    6. In the Reference Material category group, complete the following fields as required:

      Note: The options in these fields configure how the reference material displays in the final report loaded in the Report Register screen.

      • Show Reference Material—Displays the reference material in the final report.
      • Hide in Lab Job
      • Show the Actual Value for Pass / Fail—The final report displays the actual values for pass and fail instead of reporting the percentage difference from the accepted value.
      • Measurement 1—Shows the first initial measurement in the final report.
      • Measurement 2—Shows the second initial measurement in the final report when available.
      • Choose Standards—Option not currently available.
    7. In the quadrant below the Reference Material category group, complete the following fields as required:
      • Verify QC Before Approval—If selected, AssayNet LIMS displays the Data Validation Error screen when the data is approve. For more information, see View and Approve Results. Display any failed QC, and required a comment for every QC that fail in order to continue with the approving.
      • Auto Validation—If selected, the system automatically validates QC results based on predefined criteria without requiring manual review.
      • Use Split for Replicate—Enables the system to use sample splits (duplicates) as replicates for QC calculations.
      • Show QC Codes in Sample Lists—If checked, QC codes display in sample selection lists, making them easier to identify and manage.
      • Allow Calibration Bypass—Allows skipping calibration steps for certain QC scenarios where calibration is unnecessary or already validated externally.
      • QC Template—Drop-down list to select a predefined QC template that standardizes how QC in the Excel Add-in.
      • Client Sample Code—A specific code that identifies the client sample to be used for QC tracking and reporting.
      • Limit Value % for QC—Defines the allowable percentage deviation for QC comparison. A value of 0 means no deviation is permitted.
  5. Click OK.